Medical disclaimer: Educational information only, not medical advice. AcuteRejection.com is not a medical provider and does not diagnose or treat any condition. Always consult your transplant team or another qualified healthcare professional, and never change or stop anti-rejection medication on your own. If you think you have an emergency, call your local emergency number.
Official Medical & Research Organizations
- United Network for Organ Sharing (UNOS) — UNOS manages the national transplant waiting list and oversees organ allocation policy in the United States under contract with HRSA. The UNOS website provides data dashboards on transplant volumes, waiting list statistics, and post-transplant outcomes by organ type, transplant center, and year.
- Organ Procurement and Transplantation Network (OPTN) — OPTN is the national network connecting transplant hospitals, organ procurement organizations, and laboratories. The OPTN data portal provides comprehensive statistics on transplant outcomes, rejection rates, and immunosuppression protocols used at U.S. transplant centers.
- American Society of Transplantation (AST) — AST is the leading professional society for transplant medicine. AST publishes clinical practice guidelines, hosts continuing medical education, and funds research on rejection mechanisms, immunosuppression innovation, and transplant outcomes improvement.
- International Society for Heart and Lung Transplantation (ISHLT) — ISHLT maintains the world's largest registry of heart and lung transplant outcomes. The ISHLT Registry Reports provide granular data on rejection incidence, graft survival, and immunosuppression use in cardiothoracic transplantation.
Patient Support & Education
- National Kidney Foundation — Transplant Resources — The NKF provides extensive patient education on kidney transplantation including pre-transplant evaluation, understanding rejection, managing immunosuppression side effects, and staying healthy post-transplant. Includes patient-friendly explanations of creatinine, GFR, and biopsy results.
- Transplant Living (UNOS Patient Portal) — UNOS-maintained patient resource with guides on understanding your transplant, what to expect during recovery, recognizing rejection symptoms, and connecting with other transplant patients. Includes interactive tools for finding transplant centers and understanding organ allocation.
- OrganDonor.gov (HRSA) — The official U.S. government resource for organ donation registration, donor family support, and public education about the organ donation process. Understanding donation helps both recipients and families navigate the transplant system.
Clinical Guidelines & Research
- KDIGO Transplant Guidelines — Kidney Disease: Improving Global Outcomes (KDIGO) publishes the authoritative clinical practice guidelines for kidney transplant recipients, covering immunosuppression protocols, rejection monitoring, infection prophylaxis, and long-term graft management. Updated periodically by an international panel of transplant experts.
- PubMed (National Library of Medicine) — The world's largest free biomedical literature database with over 35 million citations. Search for peer-reviewed studies on acute rejection, Banff classification updates, novel immunosuppressive agents, and donor-specific antibody management. Filter by review type, publication date, and organ system.
- ClinicalTrials.gov — The NIH registry of ongoing and completed clinical trials worldwide. Search for active trials related to acute rejection treatment, novel immunosuppression regimens, tolerance induction, and transplant biomarker studies. Many trials are actively enrolling transplant recipients.
On-Site Resources
- Frequently Asked Questions — Comprehensive answers to common questions about acute rejection diagnosis, treatment, and prevention for transplant patients and families.
- Immunosuppression Guide — Detailed guide to post-transplant immunosuppressive medications including tacrolimus, mycophenolate, prednisone, and newer agents with dosing guidance and drug interaction information.
- Types of Rejection — Educational overview of hyperacute, acute cellular, antibody-mediated, and chronic rejection with explanations of mechanisms, diagnostic criteria, and treatment approaches.
- Treatment Options — Evidence-based treatment protocols for acute rejection episodes including pulse steroids, anti-thymocyte globulin, plasmapheresis, and IVIG therapy.
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